AHR Rabbit Polyclonal Antibody, 100ul Metabolic enzymes a rare autosomal recessive disorder

a rare autosomal recessive disorder

but the full-length nature of many of these variants has not been determined

at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein

but only three have been characterized to date

AHR Rabbit Polyclonal Antibody, 100ul Metabolic enzymes a rare autosomal recessive disorderThe protein encoded by this gene is a ligand activated helix loop helix transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic metabolizing enzymes such as cytochrome P450. Before ligand binding, the encoded protein is sequestered in the cytoplasm; upon ligand binding, this protein moves to the nucleus and stimulates transcription of target genes.