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Sgo2 Polyclonal Antibody, 100ul Pipette Filler The encoded protease (cathepsin G)

SKU: 895761262

4.2
USD141.00 USD165.00

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Sgo2 Polyclonal Antibody, 100ul Pipette Filler The encoded protease (cathepsin G)Cooperates with PPP2CA to protect centromeric cohesin from separase mediated cleavage in oocytes specifically during meiosis I. Has a crucial role in protecting REC8 at centromeres from cleavage by separase. During meiosis, protects centromeric cohesion complexes until metaphase II anaphase II transition, preventing premature release of meiosis specific REC8 cohesin complexes from anaphase I centromeres. Is thus essential for an accurate

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Description

The encoded protease (cathepsin G) has a specificity similar to that of chymotrypsin C

It also promotes actin assembly and membrane protrusions when overexpressed in mammalian cells

as well as retinoic acid-induced neuronal differentiation

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Sgo2 Polyclonal Antibody, 100ul Pipette Filler The encoded protease (cathepsin G)Cooperates with PPP2CA to protect centromeric cohesin from separase mediated cleavage in oocytes specifically during meiosis I. Has a crucial role in protecting REC8 at centromeres from cleavage by separase. During meiosis, protects centromeric cohesion complexes until metaphase II anaphase II transition, preventing premature release of meiosis specific REC8 cohesin complexes from anaphase I centromeres. Is thus essential for an accurate

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