HtrA2 Polyclonal Antibody, 20ul[BT-AP04279] Diagnostic Probes & Oligos The protein encoded by KCNN4

The protein encoded by KCNN4 is part of a potentially heterotetrameric voltage-independent potassium channel that is activated by intracellular calcium

Alternate splicing of CTSH results in multiple transcript variants encoding different isoforms

and SAM (sterile alpha motif) domains

at least one of which encodes an isoform that is proteolytically processed

HtrA2 Polyclonal Antibody, 20ul[BT-AP04279] Diagnostic Probes & Oligos The protein encoded by KCNN4HTRA2 encodes a serine protease. The HtrA serine peptidase 2 has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat containing 4. Nuclear