NEK1 Polyclonal Antibody, 50ul Yeast Expression This gene maps in a

This gene maps in a region that contains the BRCA1 locus which confers susceptibility to breast and ovarian cancer

Four alternatively spliced transcript variants encoding distinct isoforms have been found for this gene

This gene is located adjacent to the imprinted domain in the Prader-Willi syndrome deletion region of chromosome 15

is expressed in a variety of tissues with the highest levels in heart and pancreas

NEK1 Polyclonal Antibody, 50ul Yeast Expression This gene maps in aThe protein encoded by this gene is a serine threonine kinase involved in cell cycle regulation. The encoded protein is found in a centrosomal complex with FEZ1, a neuronal protein that plays a role in axonal development. Defects in this gene are a cause of polycystic kidney disease (PKD). Several transcript variants encoding different isoforms have been found for this gene.