HLA-DO Alpha Polyclonal Antibody, 100ul Biomatrix There are six pseudogenes of

There are six pseudogenes of this gene found on chromosomes 2

A truncated copy of this gene is found on the Y chromosome at the pseudoautosomal boundary

The TFIIIC2 complex is composed of six subunits

Polymorphisms in this gene have been linked to various human diseases| including IgA deficiency| common variable immunodeficiency| and premature ovarian failure

HLA-DO Alpha Polyclonal Antibody, 100ul Biomatrix There are six pseudogenes ofHLA DOA belongs to the HLA class II alpha chain paralogues. HLA DOA forms a heterodimer with HLA DOB. The heterodimer, HLA DO, is found in lysosomes in B cells and regulates HLA DM mediated peptide loading on MHC class II molecules. In comparison with classical HLA class II molecules, this gene exhibits very little sequence variation, especially at the protein level.