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RyR-2(Phospho Ser2808) Polyclonal Antibody, 20ul Inoculating Loops/Needles A pseudogene of MED21 is

SKU: 93189856962

4.3
PLN97.20 PLN123.20

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RyR-2(Phospho Ser2808) Polyclonal Antibody, 20ul Inoculating Loops/Needles A pseudogene of MED21 isThis gene encodes a ryanodine receptor found in cardiac muscle sarcoplasmic reticulum. The encoded protein is one of the components of a calcium channel, composed of a tetramer of the ryanodine receptor proteins and a tetramer of FK506 binding protein 1B proteins, that supplies calcium to cardiac muscle. Mutations in this gene are associated with stress induced polymorphic ventricular tachycardia and arrhythmogenic right ventricular dysplasia.

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Description

A pseudogene of MED21 is located on chromosome 8

Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups

The encoded protein can bind to both B-cell leukemia/lymphoma 3 (BCL-3) and neural precursor cell expressed| developmentally downregulated 4| (Nedd4) proteins

including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis

RyR-2(Phospho Ser2808) Polyclonal Antibody, 20ul Inoculating Loops/Needles A pseudogene of MED21 isThis gene encodes a ryanodine receptor found in cardiac muscle sarcoplasmic reticulum. The encoded protein is one of the components of a calcium channel, composed of a tetramer of the ryanodine receptor proteins and a tetramer of FK506 binding protein 1B proteins, that supplies calcium to cardiac muscle. Mutations in this gene are associated with stress induced polymorphic ventricular tachycardia and arrhythmogenic right ventricular dysplasia.

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