Human Sterol Regulatory Element-binding Protein 1, SREBF1 ELISA Kit , 96T Gloves BRE (brain and reproductive organ-expressed

BRE (brain and reproductive organ-expressed (TNFRSF1A modulator)) encodes an anti-apoptotic

Mutations of ankyrin genes lead to severe genetic diseases

Alternate splicing of this gene results in three transcript variants encoding different isoforms

It shows high transcription levels in 2 retinoblastoma cell lines and in tissues of neuroectodermal origin

Human Sterol Regulatory Element-binding Protein 1, SREBF1 ELISA Kit , 96T Gloves BRE (brain and reproductive organ-expressed[Sterol regulatory element binding protein 1]: Precursor of the transcription factor form (Processed sterol regulatory element binding protein 1), which is embedded in the endoplasmic reticulum membrane (PubMed: 32322062). Low sterol concentrations promote processing of this form, releasing the transcription factor form that translocates into the nucleus and activates transcription of genes involved in cholesterol biosynthesis and lipid homeostasis