Rat Mothers Against Decapentaplegic Homolog 3, SMAD3 ELISA Kit, 96T DNA Fragments An important paralog of this

An important paralog of this gene is UBTD1

in complex with its regulatory protein SAV1

thereby increasing binding of transcriptional activator FOXO3 to the ESR1 promoter and increasing ESR1 transcription (PubMed: 21602804)

CCL7 and CCL13 chemokines

Rat Mothers Against Decapentaplegic Homolog 3, SMAD3 ELISA Kit, 96T DNA Fragments An important paralog of thisReceptor regulated SMAD (R SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF beta and, on formation of the SMAD3 SMAD4 complex, activates transcription. Also can form a SMAD3 SMAD4 JUN FOS complex at the AP 1 SMAD site to regulate TGF beta mediated