FAK Polyclonal Antibody, 100ul[BT-AP03136] Shakers CTU1 (cytosolic thiouridylase subunit 1)

CTU1 (cytosolic thiouridylase subunit 1)

a downstream stop codon is utilized and the encoded protein extends for an additional seven amino acid residues

The encoded protein binds heterochromatin proteins and is thought to play a role in tumorigenesis

It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand

FAK Polyclonal Antibody, 100ul[BT-AP03136] Shakers CTU1 (cytosolic thiouridylase subunit 1)PTK2 encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. Focal adhesion kinase 1 is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal