Crk-L(Phospho Tyr207) Polyclonal Antibody, 50ul ROS/Nitric Oxide Detection The encoded protein does not

The encoded protein does not contain a mitochondrial targeting sequence but experimental studies confirm that it is imported into mitochondria

It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form

Intermediate length expansions of this tract increase susceptibility to amyotrophic lateral sclerosis

Calcineurin B homologous protein 1

Crk-L(Phospho Tyr207) Polyclonal Antibody, 50ul ROS/Nitric Oxide Detection The encoded protein does notThis gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS dependent fashion. It is a substrate of the BCR ABL tyrosine kinase, plays a role in fibroblast transformation by BCR ABL, and may be oncogenic.