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K1H1 Polyclonal Antibody, 20ul Modified Oligos Autoantibodies reacting with this protein

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K1H1 Polyclonal Antibody, 20ul Modified Oligos Autoantibodies reacting with this proteinThe protein encoded by this gene is a member of the keratin gene family. As a type I hair keratin, it is an acidic protein which heterodimerizes with type II keratins to form hair and nails. The type I hair keratins are clustered in a region of chromosome 17q12 q21 and have the same direction of transcription.

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Description

Autoantibodies reacting with this protein are found in the sera of patients with Sjogren syndrome and systemic lupus erythematosus

which specifically activates two members of the Rho GTPase family: rHOA and RHOB

The gene encoding for the CDYL protein localizes to chromosome 6p25

Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability

K1H1 Polyclonal Antibody, 20ul Modified Oligos Autoantibodies reacting with this proteinThe protein encoded by this gene is a member of the keratin gene family. As a type I hair keratin, it is an acidic protein which heterodimerizes with type II keratins to form hair and nails. The type I hair keratins are clustered in a region of chromosome 17q12 q21 and have the same direction of transcription.

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