IFI-16 Polyclonal Antibody, 20ul Insect Expression Integrins are heterodimeric integral membrane

Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain

Alternatively spliced transcript variants encoding multiple isoforms with 3 to 5 EGF-like repeats have been observed for ADGRE5

Infection with Epstein-Barr virus results in the overexpression of this gene

Among its related pathways are DNA Double-Strand Break Repair and Fanconi anemia pathway

IFI-16 Polyclonal Antibody, 20ul Insect Expression Integrins are heterodimeric integral membraneIFI16 encodes a member of the HIN 200 (hematopoietic interferon inducible nuclear antigens with 200 amino acid repeats) family of cytokines. The encoded protein contains domains involved in DNA binding, transcriptional regulation, and protein protein interactions. The protein localizes to the nucleoplasm and nucleoli, and interacts with p53 and retinoblastoma 1. It modulates p53 function, and inhibits cell growth in the Ras Raf signaling pathway.