TCPG Polyclonal Antibody, 20ul Sealing Film CYBB deficiency is one of

CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD)

and thus plays a role in the cell response to environmental stresses

The molecular defects in complementation groups B| C| and D all lead to a deficiency in RFX| a nuclear protein complex that binds to the X box of MHC-II promoters

This gene encodes a phosphoprotein containing six characteristic repeat motifs

TCPG Polyclonal Antibody, 20ul Sealing Film CYBB deficiency is one ofThe protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP dependent manner. The complex folds various proteins, including actin and tubulin. Alternate