IGFBP3 Polyclonal Antibody, 20ul[BT-AP04388] CellSafe™ Upon phosphorylation

Upon phosphorylation

Localized to endosomes and endoplasmic reticulum of the perinuclear region

The cytoplasmic peripheral membrane protein encoded by EZR functions as a protein-tyrosine kinase substrate in microvilli

and neonatal-onset multisystem inflammatory disease (NOMID)

IGFBP3 Polyclonal Antibody, 20ul[BT-AP04388] CellSafe™ Upon phosphorylationIGFBP3 is a member of the insulin like growth factor binding protein (IGFBP) family and encodes Insulin like growth factor binding protein 3 with an IGFBP domain and a thyroglobulin type I domain. The protein forms a ternary complex with insulin like growth factor acid labile subunit (IGFALS) and either insulin like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half life of IGFs and altering their interaction