TCF-1 Polyclonal Antibody, 50ul Low-speed Centrifuges This heterodimer binds E-box enhancer

This heterodimer binds E-box enhancer elements upstream of Period (PER1| PER2| PER3) and Cryptochrome (CRY1| CRY2) genes and activates transcription of these genes

resulting in expression of a chimeric protein

This complex is crucial for NPC stability and proper assembly

and thus is thought to be an early event in Alzheimer disease pathogenesis

TCF-1 Polyclonal Antibody, 50ul Low-speed Centrifuges This heterodimer binds E-box enhancerTranscription factor 7 encoded by TCF7 is a transcriptional activator that plays an important role in lymphocyte differentiation. This gene is expressed predominantly in T cells. The transcription factor 7 can bind an enhancer element and activate the CD3E gene, and it also may repress the CTNNB1 and TCF7L2 genes through a feedback mechanism. Several transcript variants encoding different isoforms have been found for this gene.