MCLN2 Rabbit Polyclonal Antibody, 50ul Biomatrix This encoded protein is a

This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin

Mutations in this gene are a cause of colorectal cancer (CRC)

an essential protein required to the initiation of DNA replication

The TRRAP/TIP60 complex acetylates nucleosomal histones important for transcriptional regulation

MCLN2 Rabbit Polyclonal Antibody, 50ul Biomatrix This encoded protein is aMucolipins constitute a family of cation channel proteins with homology to the transient receptor potential superfamily. In mammals the mucolipin family includes 3 members MCOLN1 (MIM 605248) MCOLN2 and MCOLN3 (MIM 607400) that exhibit a common 6 membrane spanning topology. Homologs of mammalian mucolipins exist in Drosophila and C. elegans. Mutations in the human MCOLN1 gene cause mucolipodosis IV (MIM 262650) (Karacsonyi et al. 2007