HDAC7 Polyclonal Antibody, 100ul Antibodies Mediates AURKA localization to spindle
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HDAC7 Polyclonal Antibody, 100ul Antibodies Mediates AURKA localization to spindleHistones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation deacetylation alters chromosome structure and affects transcription factor access to DNA. Histone deacetylase 7 encoded by HDAC7 has sequence homology to members of the histone deacetylase family. HDAC7 is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT.
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