SIR4 Polyclonal Antibody, 100ul Nucleic Acid Amplification Heterozygous loss-of-function mutations in KLF1

Heterozygous loss-of-function mutations in KLF1 result in the dominant In (Lu) blood phenotype

prostate cancers

The protein associates with hamartin in a cytosolic complex

Acyl-coenzyme A thioesterase 4 is an enzyme encoded by the ACOT4 gene in humans and is mapped to chromosome 14

SIR4 Polyclonal Antibody, 100ul Nucleic Acid Amplification Heterozygous loss-of-function mutations in KLF1This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular