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IKK gamma(Phospho Ser376) Polyclonal Antibody, 100ul Thermo Mix PRKD1 is a serine/threonine kinase

SKU: 96924790617

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IKK gamma(Phospho Ser376) Polyclonal Antibody, 100ul Thermo Mix PRKD1 is a serine/threonine kinaseThis gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex which activates NF kappaB resulting in activation of genes involved in inflammation immunity cell survival and other pathways. Mutations in this gene result in incontinentia pigmenti hypohidrotic ectodermal dysplasia and several other types of immunodeficiencies. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome.

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Description

PRKD1 is a serine/threonine kinase that regulates a variety of cellular functions

TIMP2 is a member of the TIMP gene family

and typing for these polymorphisms is routinely done for bone marrow transplantation

Knockdown studies in zebrafish suggest that this gene is essential for normal inner ear function

IKK gamma(Phospho Ser376) Polyclonal Antibody, 100ul Thermo Mix PRKD1 is a serine/threonine kinaseThis gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex which activates NF kappaB resulting in activation of genes involved in inflammation immunity cell survival and other pathways. Mutations in this gene result in incontinentia pigmenti hypohidrotic ectodermal dysplasia and several other types of immunodeficiencies. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome.

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