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Insulin R Polyclonal Antibody, 100ul[BT-AP04566] Primary Antibodies Significantly overexpressed in many lung

SKU: 97379079168

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Insulin R Polyclonal Antibody, 100ul[BT-AP04566] Primary Antibodies Significantly overexpressed in many lungINSR encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the

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Description

Significantly overexpressed in many lung cancer samples

Does not activate JNK1/MAPK8 pathway

Proteins of this family are defined by a vacuolar protein sorting 10 domain at the N-terminus

The product of this gene is one of the four subunits of an enzyme which belongs to the serine/threonine protein kinase family| and to the Ca(2+)/calmodulin-dependent protein kinase subfamily

Insulin R Polyclonal Antibody, 100ul[BT-AP04566] Primary Antibodies Significantly overexpressed in many lungINSR encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the

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