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VRK1 Polyclonal Antibody, 20ul DNA Synthesis This kinase can be activated

SKU: 98135447100

4.0
USD97.20 USD135.20

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VRK1 Polyclonal Antibody, 20ul DNA Synthesis This kinase can be activatedThis gene encodes a member of the vaccinia related kinase (VRK) family of serine threonine protein kinases. This gene is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, thymus, fetal liver, and carcinomas. Its protein localizes to the nucleus and has been shown to promote the stability and nuclear accumulation of a transcriptionally active p53 molecule and, in vitro, to phosphorylate

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Description

This kinase can be activated by TNF-alpha

Its interaction with nuclear receptors is independent of the AF2 domain on the receptors

Belongs to the small leucine-rich proteoglycan (SLRP) family

Mutations in this gene have been associated with predisposition to prostate cancer and this gene is a candidate for the hereditary prostate cancer 1 (HPC1) allele

VRK1 Polyclonal Antibody, 20ul DNA Synthesis This kinase can be activatedThis gene encodes a member of the vaccinia related kinase (VRK) family of serine threonine protein kinases. This gene is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, thymus, fetal liver, and carcinomas. Its protein localizes to the nucleus and has been shown to promote the stability and nuclear accumulation of a transcriptionally active p53 molecule and, in vitro, to phosphorylate

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