CITE2 Polyclonal Antibody, 20ul Gene Synthesis Core binding factor (CBF) is

Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters

three pseudogenes are located on chromosomes 9

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some members of this family may be involved in embryogenesis

CITE2 Polyclonal Antibody, 20ul Gene Synthesis Core binding factor (CBF) isThe protein encoded by this gene inhibits transactivation of HIF1A induced genes by competing with binding of hypoxia inducible factor 1 alpha to p300 CH1. Mutations in this gene are a cause of cardiac septal defects. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.