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Chowdhury, G.M

Over 26 weeks, cagrilintide demonstrated dose-dependent weight loss with the 4.5 mg dose achieving approximately 10.8% reduction compared to 3.0% with placebo

J Pharmacol Exp Ther 369:129141 [DOI] [PubMed] [Google Scholar] Gergs U, Jung F, Buchwalow IB, Hofmann B, Simm A, Treede H, Neumann J (2017) Pharmacological and physiological assessment of serotonin formation and degradation in isolated preparations from mouse and human hearts

2-Chloro-N-(4-(prop-2-yn-1-yloxy)phenyl)acetamide ( 19 ) Yield 79%, white solid 1 H NMR (500 MHz, CDCl 3 ) 8.38 (bs, 1H), 7.357.27 (m, 2H), 7.056.96 (m, 2H), 4.84 (d, J = 5.2 Hz, 2H), 4.73 (d, J = 2.4 Hz, 2H), 4.65 (s, 2H), 2.56 (t, J = 2.4 Hz, 1H) ppm