Tanshinone I Size:2mg solid A single-dose administration to rats

A single-dose administration to rats the LD50 is >2000 mg/kg bwt by the oral route

[Epub ahead of print] PubMed PMID: 27444277

Remdesivir O-desphosphate acetonide impurity (analogue 21) is a 2′

7 nM against HSP90β and of 7

Tanshinone I Size:2mg solid A single-dose administration to ratsTanshinone I is a diterpene with anticancer, antidiabetic, and neuroprotective properties. It inhibits proliferation in a variety of cancer cell lines, including KB VCR, MCF 7 ADR, and K562 A02 multidrug resistance cell lines. It inhibits topoisomerase I and topoisomerase II mediated supercoiled DNA relaxation activity and inhibits proliferation of H358 IR and H157 IR radioresistant lung cancer cells. It reduces plasma levels of total cholesterol,