VER-50589 te salt 23(3):427-40

23(3):427-40

Ezogabine works primarily as a potassium channel opener—that is

Smiles: CC1NC(=O)CC(C=1C(=O)NC1C=C2C=NNC2=CC=1F)C1C=CC(=CC=1)C(F)(F)F

C(C1NCCN=1)C1=CC=CC2=CC=CC=C12

VER-50589 te salt 23(3):427-40VER 50589 is a potent Hsp90 inhibitor. VER 50589 inhibits Hsp90 with an IC50 value of 21 nM. It produces a mean cellular antiproliferative GI50 value of 78 nM when tested against a human cancer cell line panel. VER 50589 shows favorable pharmacokinetics and impairs tumor growth in animals. Product information CAS Number: 747413 08 7 Molecular Weight: 388. 80 Formula: C19H17ClN2O5 Synonym: VER 50589 VER50589 Chemical Name: 5 (5 chloro 2,4