UNC2881 Catalog No.:M9285-10 Solubility: DMSO : 25 mg/mL

Solubility: DMSO : 25 mg/mL (105

Smiles: COC1=CC=CC=C1NC(=O)C(CC)SC1=NC2=C(N=N1)C1=CC=CC=C1N2CC

7 and 110 fold selectivity compared to wt-RET and KDR

Miglitol is an oral anti-diabetic drug that acts by inhibiting the ability of the patient to break down complex carbohydrates into glucose

UNC2881 Catalog No.:M9285-10 Solubility: DMSO : 25 mg/mLUNC2881 is a potent Mer kinase inhibitor. UNC2281 inhibits steady state Mer kinase phosphorylation with an IC50 value of 22 nM. Treatment with UNC2281 is also sufficient to block EGF mediated stimulation of a chimeric receptor containing the intracellular domain of Mer fused to the extracellular domain of EGFR. In addition, UNC2881 potently inhibits collagen induced platelet aggregation, suggesting that this class of inhibitors may have utility for