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Vinflunine Size:Solid 2 mg β-elemene can inhibit cell proliferation

SKU: 20806500379

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SEK110.00 SEK143.00

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Vinflunine Size:Solid 2 mg β-elemene can inhibit cell proliferationVinflunine is a bi fluorinated derivative of the semi synthetic vinca alkaloid vinorelbine with antitubulin, antineoplastic, and antiangiogenic activities. Vinflunine inhibits tubulin assembly without any stablization of assembled microtubules at concentrations comparable to those of other vinca alkaloids such as vincristine, vinblastine and vinorelbine; this effect on microtubule dynamics results in cell cycle arrest in mitosis and apoptosis.

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Description

β-elemene can inhibit cell proliferation

Molecular Weight: 582

with much higher IC50 values (40 nM–170 nM)

(2014) Science 344(6183):527-32

Vinflunine Size:Solid 2 mg β-elemene can inhibit cell proliferationVinflunine is a bi fluorinated derivative of the semi synthetic vinca alkaloid vinorelbine with antitubulin, antineoplastic, and antiangiogenic activities. Vinflunine inhibits tubulin assembly without any stablization of assembled microtubules at concentrations comparable to those of other vinca alkaloids such as vincristine, vinblastine and vinorelbine; this effect on microtubule dynamics results in cell cycle arrest in mitosis and apoptosis.

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