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Lonafarnib - CAS# 193275-84-2 702 1380548-02-6

Lonafarnib - CAS# 193275-84-2 702 1380548-02-6

Name: Lonafarnib - CAS# 193275-84-2 702 1380548-02-6
Brand: matisco.be
SKU: 28633038125
Price: 113.05 USD
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SKU: 28633038125

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Lonafarnib - CAS# 193275-84-2 702 1380548-02-6Lonafarnib is a farnesyl transferase inhibitor. Structurely, it is also a synthetic tricyclic derivative of carboxamide with antineoplastic properties. Lonarfanib binds to and inhibits farnesyl transferase, an enzyme involved in the post translational modification and activation of Ras proteins. Ras proteins participate in numerous signalling pathways (proliferation, cytoskeletal organization), and play an important role in oncogenesis. Mutated ras

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Description

1380548-02-6

At 5 μM it directly inhibits DUB activity of USP9x

Smiles: COC1C2C=COC=2C(OC[C@@H](O)C(C)(C)O)=C2OC(=O)C=CC2=1

H2O/c12-10(14)16-6-9(7-17-11(13)15)8-4-2-1-3-5-8

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