AMG-208 - CAS# 1002304-34-8 K-4827 Tosylate 18)3)23(2)10-8-16(25)12-15(23)13-20(22)26/h14-20
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AMG-208 - CAS# 1002304-34-8 K-4827 Tosylate 18)3)23(2)10-8-16(25)12-15(23)13-20(22)26/h14-20AMG 208 is a selective small molecule inhibitor of the proto oncogene c Met with potential antineoplastic activity. c Met inhibitor AMG 208 inhibits the ligand dependent and ligand independent activation of c Met, inhibiting its tyrosine kinase activity, which may result in cell growth inhibition in tumors that overexpress c Met. C Met encodes the hepatocyte growth factor receptor tyrosine kinase, plays an important role in epithelial cell
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