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WP1130 (Degrasyn) - Deubiquitinylating Enzyme (DUB) Inhibitor. CAS# 856243-80-6 426 1457983-28-6

WP1130 (Degrasyn) - Deubiquitinylating Enzyme (DUB) Inhibitor. CAS# 856243-80-6 426 1457983-28-6

Name: WP1130 (Degrasyn) - Deubiquitinylating Enzyme (DUB) Inhibitor. CAS# 856243-80-6 426 1457983-28-6
Brand: matisco.be
SKU: 51407012133
Price: 39.00 USD
Availability: InStock
Rating: 4.7641 (27 reviews)

SKU: 51407012133

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USD39.00 USD83.00

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WP1130 (Degrasyn) - Deubiquitinylating Enzyme (DUB) Inhibitor. CAS# 856243-80-6 426 1457983-28-6WP1130 (Degrasyn), CAS No. 856243 80 6, is a cell permeable, potent and selective inhibitor of the deubiquitinylating enzymes (DUBs). At 5 M it directly inhibits DUB activity of USP9x, USP5, USP14, UCH L1, and UCH37, but not UCH L3, resulting in downregulation of antiapoptotic and upregulation of proapoptotic proteins, such as MCL 1 and p53. WP1130 suppresses Bcr Abl, JAK2 transducer (without affecting 20S proteasome) and activator of transcription

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Description

1457983-28-6

Tamatani T

Stoelben S

colon weight per unit length in the control group is more than twice that in the normal group

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