PF-04217903 (methanesulfonate) Catalog No.:M10134-2 In vivo and in vitro

In vivo and in vitro ovarian carcinoma growth inhibition by a phosphatidylinositol 3-kinase inhibitor (LY294002)

Ro 61-8048 could be a new avenue to reduce neuronal loss in brain ischemia

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Van Glabbeke M

PF-04217903 (methanesulfonate) Catalog No.:M10134-2 In vivo and in vitroPF 04217903 is a MET tyrosine kinase inhibitor, is also a n orally bioavailabe, small molecule tyrosine kinase inhibitor of the proto oncogene c Met (hepatocyte growth factor receptor [HGFR]) with potential antineoplastic activity. c Met inhibitor PF 04217903 selectively binds to and inhibits c Met, disrupting the c Met signaling pathway, which may result in the inhibition of tumor cell growth, migration and invasion of tumor cells, and the induction