Brinzolamide Size:Solid 10 mg PubMed Central PMCID: PMC4063656

PubMed Central PMCID: PMC4063656

Chemical Name: lithium(1+) 3-{[2-(pyridin-2-yl)-6-(2

C[C@H](CSC(=O)C1C=CC=CC=1)C(=O)N1C[C@H](C[C@H]1C([O-])=O)SC1C=CC=CC=1

InChi: InChI=1S/C24H31N3O10/c28-19-5-4-18(22(31)26-19)27-23(32)16-2-1-3-17(21(16)24(27)33)25-7-9-35-11-13-37-15-14-36-12-10-34-8-6-20(29)30/h1-3

Brinzolamide Size:Solid 10 mg PubMed Central PMCID: PMC4063656Brinzolamide is a carbonic anhydrase inhibitor used to lower intraocular pressure in patients with open angle glaucoma or ocular hypertension. Inhibition of carbonic anhydrase in the ciliary processes of the eye decreases aqueous humor secretion and thus lowers the intraocular pressure in the anterior chamber, presumably by reducing the rate of formation of bicarbonate ions with subsequent reduction in sodium and fluid transport; this alleviates the