Fenretinide - CAS# 65646-68-6 127 5 day) potently and selectively

5 day) potently and selectively inhibits IL-17 and IL-22 levels

4SC-202 was used at 10µM final concentration in various in vitro assays

PMID: 23486186

inhibiting prolyl hydroxylation and increasing HIF-1α levels in cells (IC50 ~5

Fenretinide - CAS# 65646-68-6 127 5 day) potently and selectivelyFenretinide, CAS No. 65646 68 6, is an orally active synthetic phenylretinamide analogue of retinol (vitamin A) with potential antineoplastic and chemopreventive activities. Fenretinide binds to and activates retinoic acid receptors (RARs), thereby inducing cell differentiation and apoptosis in some tumor cell types. This agent also inhibits tumor growth by modulating angiogenesis associated growth factors and their receptors and exhibits retinoid