A-674563 - CAS# 552325-73-2 Size:Solid 2 mg 5-a]pyrimidin-3-yl)benzamide

5-a]pyrimidin-3-yl)benzamide

InChi: InChI=1S/C6H12F2N2O2

RN-1 exhibits good brain penetration and retention

with VLX1570 is lethal to ibrutinib- or bortezomib-resistant Waldenstrom macroglobulinemia tumor cells

A-674563 - CAS# 552325-73-2 Size:Solid 2 mg 5-a]pyrimidin-3-yl)benzamideA 674563 is a potent, orally available Akt1 inhibitor with an IC50 value of 11nM. Also displays activity against PKA and CDK2 with IC50 values of 16nM and 46nM respectively. Product information CAS Number: 552325 73 2 Molecular Weight: 358. 44 Formula: C22H22N4O Synonym: A 674563 A674563 Chemical Name: (2S) 1 {[5 (3 methyl 2H indazol 5 yl)pyridin 3 yl]oxy} 3 phenylpropan 2 amine Smiles: CC1NN=C2C=CC(=CC2=1)C1=CN=CC(=C1)OC[C@@H](N)CC1C=CC=CC=1