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BRAF inhibitor - CAS# 918505-61-0 10597 SF-1670 also elevates Akt phosphorylation

BRAF inhibitor - CAS# 918505-61-0 10597 SF-1670 also elevates Akt phosphorylation

Name: BRAF inhibitor - CAS# 918505-61-0 10597 SF-1670 also elevates Akt phosphorylation
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SKU: 88124394695
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BRAF inhibitor - CAS# 918505-61-0 10597 SF-1670 also elevates Akt phosphorylationVemurafenib Analog is a potent BRAF inhibitor and the isomer of Vemurafenib. Vemurafenib, also known as PLX4032, RG7204 or RO5185426, is an orally bioavailable, ATP competitive, small molecule inhibitor of BRAF(V600E) kinase with potential antineoplastic activity. Vemurafenib received FDA approval for the treatment of late stage melanoma on August 17, 2011. Product information CAS Number: 918505 61 0 Molecular Weight: 456. 47 Formula: C22H18F2N4O3S

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Description

SF-1670 also elevates Akt phosphorylation in murine cells

also known as XL-765 and SAR245409

both basal and IGF stimulated Akt1 and Akt2 phosphorylation are inhibited in mouse lung

166518-60-1

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