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INCB024360 analogue(IDO-IN-1) - CAS# 914471-09-3 size:2mg solid J Mol Neurosci

INCB024360 analogue(IDO-IN-1) - CAS# 914471-09-3 size:2mg solid J Mol Neurosci

Name: INCB024360 analogue(IDO-IN-1) - CAS# 914471-09-3 size:2mg solid J Mol Neurosci
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INCB024360 analogue(IDO-IN-1) - CAS# 914471-09-3 size:2mg solid J Mol NeurosciINCB14943, also known as INCB024360 analog, IDO5L and IDO IN 2 with CAS#914471 09 3, CAS No. 914471 09 3, is a potent and orally available hydroxyamidine and inhibitor of indoleamine 2, 3 dioxygenase (IDO1) with potential immunomodulating and antineoplastic activities. INCB024360 analog is a potent (HeLa IC50=19 nM) competitive inhibitor of IDO. Testing of INCB024360 analog in mice demonstrated pharmacodynamic inhibition of IDO, as measured by

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J Mol Neurosci

PubMed PMID: 30655275

PF-475 significantly diminishes ROT-induced ROS generation to a similar extent to cells exposed to PF-475 alone

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