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Ro-3306 pafenac 841290-80-0 (Tamatinib free base)

Ro-3306 pafenac 841290-80-0 (Tamatinib free base)

Name: Ro-3306 pafenac 841290-80-0 (Tamatinib free base)
Brand: matisco.be
SKU: 92880393976
Price: 85.00 USD
Availability: InStock
Rating: 4.0144 (5 reviews)

SKU: 92880393976

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EUR85.00 EUR110.00

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Ro-3306 pafenac 841290-80-0 (Tamatinib free base)RO 3306 is a CDK1 inhibitor with potential anticancer activity. Treatment of growing AML cells with RO 3306 induced G2 M phase cell cycle arrest and apoptosis in a dose and time dependent manner. RO 3306 downregulated expression of the antiapoptotic proteins Bcl 2 and survivin and blocked p53 mediated induction of p21 and MDM2. RO 3306 actively enhances downstream p53 signaling to promote apoptosis. Product information CAS Number: 872573 93 8

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Description

841290-80-0 (Tamatinib free base)

2414591-05-0

CAS Number: 81624-55-7

QAW039 was also a potent inhibitor of PGD2-induced cytokine release in human Th2 cells

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