GNF-2 - CAS# 778270-11-4 0228 InChiKey: FXHHASJVTYRJHH-UHFFFAOYSA-N

InChiKey: FXHHASJVTYRJHH-UHFFFAOYSA-N

PARP inhibitor with selectivity toward ADP-ribosyltransferase ARTD3/PARP3

Formula: C27H28N4O3S2

BG45 alone and in combination with bortezomib triggers significant tumor growth inhibition in vivo in a murine xenograft model of human MM

GNF-2 - CAS# 778270-11-4 0228 InChiKey: FXHHASJVTYRJHH-UHFFFAOYSA-NGNF 2, CAS No. 778270 11 4, is an allosteric inhibitor of Bcr abl tyrosine kinase activity (IC50 = 267 nM); inhibits proliferation and induces apoptosis in Bcr abl expressing cells. Selective for Bcr abl over a panel of serine, threonine and tyrosine kinases. Non ATP competitive. Product information CAS Number: 778270 11 4 Molecular Weight: 374. 32 Formula: C18H13F3N4O2 Chemical Name: 3 (6 {[4 (trifluoromethoxy)phenyl]amino}pyrimidin 4 yl)benzamide