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Conversely, some studies show that a deficiency in vitamin B12 may cause appetite loss, potentially leading to weight loss if left untreated ( If youre low or deficient in B12, your healthcare provider will likely recommend oral vitamin B12 supplements or injections to increase your blood levels ( summary Low levels of vitamin B12 can cause megaloblastic anemia, which is characterized by shortness of breath, headaches, and fatigue

Published animal research uses 10 g/kg daily the allometric human equivalent is roughly 200300 g/day

What to do if B12 drops despite supplementation If you are taking semaglutide methylcobalamin and your B12 levels still decline, several options exist: Switch to injectable B12 supplementation

It works as a very selective GLP-1 receptor agonist and is very similar to human GLP-1 (94% similarity)