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For metabolic analysis of cultured cancer cells and tumours, frozen tumour tissue was homogenized in 80% methanol containing 20 mM NEM using a Precellys cold tissue homogenizer (Bertin) at a ratio of 20 mg tissue to 1 ml solvent

Ann N Y Acad Sci (2009) 1170:914.10.1111/j.1749-6632.2009.04485.x 131 SteinertREGerspachACGutmannHAsarianLDreweJBeglingerC

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For example, fucoxanthin was found to induce a G0/G1 phase block in cancer cells while upregulating GADD45, a DNA repair gene regulated by p53, which helps maintain genomic stability and reduce cancer risk (44)