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With a 5-fold increase in dose, the steady-state exposures for silybin A and silybin B increased 11-fold and 38-fold, respectively, suggesting non-linear pharmacokinetics

A 3 l aliquot of each sample was injected for LC-MSMS analysis

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Updated on April 7, 2023 Article Summary Irritable bowel syndrome is associated with a wide range of uncomfortable symptoms that are poorly controlled with conventional therapies Although no single cause of IBS has been identified, researchers believe that inflammation plays a significant role