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Leffetto appare pi evidente nelle persone con sovrappeso o obesit , mentre nelle donne normopeso minimo

The reconstitution and administration of injectable medicines in the UK must be performed by, or under the direct supervision of, a qualified healthcare professional, following the product's SmPC and in accordance with NHS and NPSA guidance on the safer use of injectable medicines

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61 When administered as 3 or 10 mg/kg intravenously immediately before reperfusion in a canine coronary occlusion-reperfusion model of myocardial infarction, a significant dose-dependent reduction in infarct size was observed